A new study finds that antibodies that exist in the joints before the onset of rheumatoid arthritis can cause pain even in the absence of arthritis. Researchers believe that the finding can represent a general mechanism in autoimmunity and that the results can facilitate the development of new ways of reducing non-inflammatory pain caused by rheumatoid arthritis and other autoimmune diseases.
Researchers have developed a rapid and reliable new method to continuously monitor sickle cell disease using a microfluidics-based electrical impedance sensor. This novel technology can characterize the dynamic cell sickling and unsickling processes in sickle blood without the use of microscopic imaging or biochemical markers. The technology is being developed with the hope of providing patients with a portable, standalone sensor to conveniently self-monitor the hematological parameters of their disease and evaluate their risk of vaso-occlusion.
Researchers have reported the first case of successful, long-term relief of chronic refractory shoulder pain in a wheelchair user with spinal cord injury following a single injection of autologous, micro-fragmented adipose tissue.