I've had Fibromyalgia for 4 years now. Triggered by a bout of Human Parvovirus (Slapface) virtually overnight.
As a male, my pain levels and general symptoms are less than those of women that I know with this condition, as fits with the descriptions in the relevant literature.
I started using SAMe 400 twice a day 2 years ago when I was under a lot of stress at work and wanted to avoid the usual pharmaceuticals prescribed for that particular condition. I have a very good doctor who made the decision to prescribe a trial of SAMe 400 before heading down the path of the standard drugs. To my great surprise, not only did it work extremely well in relation to my stress and mild depression issues, but my pain levels dropped by about 30%. We are all different in a biological sense and I do know people who find it makes no difference to their condition. But for me its been absolutely brilliant. I appear to get no side effects and it has improved my quality of life to a large degree.